The hyaluronidase enzyme is contained within the acrosome (a cap-like structure on the sperm's head) and is released during the acrosome reaction, which occurs when the sperm reaches the ovum. This enzyme helps the sperm to penetrate the layers surrounding the egg, specifically by breaking down the hyaluronic acid in the extracellular matrix of the cumulus oophorus (follicle cell layer), and potentially playing a role in breaking through the zona pellucida. This action is essential for the sperm to reach and fertilize the egg.
The function of the hyaluronidase enzyme is:
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