A 25-year-old gentleman presented with a 10 days history of fever sore throat and lymphadenopathy. He also had hepatosplenomegaly. His Hb was 14g/dl, few atypical lymphocytes were seen on peripheral smear. LFTs were also deranged. What test should be performed next?

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A 25-year-old gentleman presented with a 10 days history of fever sore throat and lymphadenopathy. He also had hepatosplenomegaly. His Hb was 14g/dl, few atypical lymphocytes were seen on peripheral smear. LFTs were also deranged. What test should be performed next? Answer: Epstein-Barr virus infection

The presentation is classical for Infectious Mononucleosis (EBV). The best next step is to perform a heterophile antibody test (Monospot) or EBV serology to confirm the diagnosis.

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This question is part of 🧬 Biochemistry within the broader 🧬 Medical Science subject and appears in the SPSC – Sindh Public Service Commission preparation collection. Reviewing the answer together with nearby questions helps reinforce the underlying concept and identify how it may appear in competitive exams.

A 25-year-old gentleman presented with a 10 days history of fever sore throat and lymphadenopathy. He also had hepatosplenomegaly. His Hb was 14g/dl, few atypical lymphocytes were seen on peripheral smear. LFTs were also deranged. What test should be performed next?

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