The beta-blocker with the least entry into the central nervous system (CNS) is atenolol, a hydrophilic (water-soluble) beta-blocker that has a low ability to cross the blood-brain barrier compared to lipophilic (fat-soluble) beta-blockers. This property results in a lower incidence of CNS side effects such as nightmares, hallucinations, and dizziness.
Betablocker with least entry into CNS is ____?
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