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The most common cause of high cardiac output hypotension is _____?

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The most common cause of high cardiac output hypotension is _____? Answer: Sepsis

Widespread infection leads to release of endotoxins and inflammatory mediators that cause systemic vasodilation, capillary leakage, and decreased systemic vascular resistance. Despite an initially high cardiac output, the patient experiences hypotension due to severe vasodilation and maldistribution of blood flow.

Question context

This question is part of 🦠 Microbiology within the broader 🧬 Medical Science subject and appears in the SPSC – Sindh Public Service Commission preparation collection. Reviewing the answer together with nearby questions helps reinforce the underlying concept and identify how it may appear in competitive exams.