Which of the following are causes of bilateral spastic paraparesis?

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Which of the following are causes of bilateral spastic paraparesis? Answer: Vitamin B12 deficiency

Vitamin B12 deficiency can cause subacute combined degeneration of the spinal cord, affecting corticospinal and posterior column pathways. This may produce bilateral weakness, spasticity, sensory abnormalities, and other neurological manifestations.

Question context

This question is part of 🧬 Biochemistry within the broader 🧬 Medical Science subject and appears in the BPSC – Balochistan Public Service Commission preparation collection. Reviewing the answer together with nearby questions helps reinforce the underlying concept and identify how it may appear in competitive exams.