A chronic history of bloody diarrhea strongly suggests inflammatory bowel disease (IBD) such as ulcerative colitis or Crohn’s disease. The gold standard investigation to confirm the diagnosis is colonoscopy with biopsy, which allows direct visualization of mucosal changes and histopathological confirmation.
A 30-year-old man presented with a 2-month history of bloody diarrhea. The best investigation to confirm the diagnosis is ____?
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